Investigator: Viola Lias Conover

Facility: St. Lukes Medical Center

Patient Code: # A

Date of Study: 10/3/96 - 1/16/97

The patient is a 56 year old male with venous insufficiency. Both lower legs were weepy and edematous. The pitting edema varied from day to day. He developed a superficial ulcer of the left lower leg measuring 9.2 cm x 9.3 cm, which drained serous to serosanguineous drainage. The ulcer was painful when cleansed or touched. There was also intense itching sensations to the legs.

For 6 months, several different treatments failed to heal the ulcer. On 10/10/96 treatment was started by first cleansing the lower leg with whirlsol solution and then applying Calmoseptine Ointment to the wound on a 4x4 gauze daily. The lower leg was then wrapped in tubigrip for compression. By 1/16/97 the ulcer was healed. Itching is also relieved when Calmoseptine Ointment is used. When treatment is stopped the patient's ulcer recurs along with the itching. He is now maintained for 1-1/2 years with this treatment and the ulcer remains healed.

Left Leg, # A, 9/5/96


Left Leg, # A, 10/17/96

DAY 42

Left Leg, # A, 10/24/96

DAY 49

Left Leg, # A, 1/16/97

DAY 133